Applications

APPLICATIONS

• Measurement of masses of intact proteins for quality control.
• Gel-purified protein identification by peptide mass fingerprinting and peptide fragmentation.
• De novo sequencing of peptides for protein identification.
• Quantification of differential protein expression by 2D-differential gel electrophoresis (DIGE).
• Quantification of differential protein expression by gel-free proteomics and 2D-LC-MS (iTraq, ICAT…).
• Identification of sites of covalent modification by collision-induced dissociation (CID) fragmentation of peptides or by electron transfer dissociation of peptides (ETD).